"Your drugs made me gay!"

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A 51-year-old Frenchman says the drug he was taking to combat his Parkinson’s Disease turned him into a “compulsive gay sex addict.”

He says the GlaxoSmithKline drug Requip, which Didier Jambart took between 2003-2005 was to blame, and he’s suing.

Jambart claimed he was raped when engaging in risky behaviours, and even began exposing himself on the internet and cross-dressing, reports CBS News.

The married father of two also lost his family’s life savings on internet gambling, and tried to commit suicide three times following has actions which he says he was unable to control.

A warning label on Requip now says some of its users “developed gambling problems or other intense urges or behaviors that were compulsive or unusual for them, such as increased sexual urges or behaviors,” but that warning was displayed a year after Jambart stopped taking the drug.

He is seeking $610,000 US dollars.

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ammonite

ammonite said on the 1st Feb, 2011

no it's not necessarily crap!

http://www.ncbi.nlm.nih.gov/pubmed/19339647

Mayo Clin Proc. 2009 Apr;84(4):310-6.
Frequency of new-onset pathologic compulsive gambling or hypersexuality after drug treatment of idiopathic Parkinson disease.

Bostwick JM, Hecksel KA, Stevens SR, Bower JH, Ahlskog JE.

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA. bostwick.john@mayo.edu

Comment in:
Mayo Clin Proc. 2009 Sep;84(9):846-7; author reply 847.

Abstract

OBJECTIVE: To determine the frequency of new-onset compulsive gambling or hypersexuality among regional patients with Parkinson disease (PD), ascertaining the relationship of these behaviors to PD drug use.

PATIENTS AND METHODS: We retrospectively reviewed the medical records of patients from 7 rural southeastern Minnesota counties who had at least 1 neurology appointment for PD between July 1, 2004, and June 30, 2006. The main outcome measure was compulsive gambling or hypersexuality developing after parkinsonism onset, including the temporal relationship to PD drug use.

RESULTS: Of 267 patients with PD who met the study inclusion criteria, new-onset gambling or hypersexuality was documented in 7 (2.6%). All were among the 66 patients (10.6%) taking a dopamine agonist. Moreover, all 7 (18.4%) were among 38 patients taking therapeutic doses (defined as >/=2 mg of pramipexole or 6 mg of ropinirole daily). Behaviors were clearly pathologic and disabling in 5: 7.6% of all patients taking an agonist and 13.2% of those taking therapeutic doses. Of the 5 patients, 2 had extensive treatment for what was considered a primary psychiatric problem before the agonist connection was recognized.

CONCLUSION: Among the study patients with PD, new-onset compulsive gambling or hypersexuality was documented in 7 (18.4%) of 38 patients taking therapeutic doses of dopamine agonists but was not found among untreated patients, those taking subtherapeutic agonist doses, or those taking carbidopa/levodopa alone. Behaviors abated with discontinuation of agonist therapy or dose reduction. Because this is a retrospective study, cases may have been missed, and hence this study may reflect an underestimation of the true frequency. Physicians who care for patients taking these drugs should recognize the drug's potential to induce pathologic syndromes that sometimes masquerade as primary psychiatric disease.

PMID: 19339647 [PubMed - indexed for MEDLINE]PMCID: PMC2665974Free PMC Article

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